Clinical impact through AI Assisted MS care
The CLAIMS project aims to address the urgent need for more data-driven and personalized care for people with MS (pwMS). To this end, our mission is to develop, validate, and seek regulatory approval for a companion platform that provides a holistic view of each patient by visualizing both existing and new biomarker data, as well as predict disease trajectories under different treatment scenarios. Powered by deep-learning-based disease subtyping and progression models, this platform aims to enhance the precision of MS care, extending the patients’ quality-adjusted life years, and reducing the economic burden on both individuals and society.
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Development of new measurement tools for biomarkers to better disentangle Progression Independent of Relapse Activity (PIRA) and Relapse Associated Worsening (RAW) based on MRI and digital health tools.
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Integration of the measurement tools and AI-based models into a companion diagnostic platform, which can be integrated in the clinical workflow.
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Validation and submission for regulatory approval of the companion diagnostic platform to ensure a sustainable adoption in the market.
News
CLAIMS consortium gathers in Baveno for the 4th General Assembly – Advancing the future of AI-assisted MS care
The CLAIMS consortium convened its 4th General Assembly (GA) on November 12, 2025, in the scenic town of Baveno, Italy. The event was a hybrid meeting, combining the face-to-face gathering in Baveno with online attendance, bringing together partners united by one mission: accelerating AI-enabled innovations for multiple sclerosis (MS) care.…
RECLAIM study protocol is published – cohort update
As we dive into the second half of 2025, we are excited to share the collective progress made by the CLAIMS consortium in the RECLAIM clinical study (NCT06280755). One of the key milestones we are proud to announce is the peer-reviewed publication of the RECLAIM study protocol: https://doi.org/10.3389/fneur.2025.1557947 RECLAIM STUDY…
Quantifying smouldering pathology – One scan at a time
A primary objective of CLAIMS is to develop tools that enhance the monitoring of disease progression in patients with Multiple Sclerosis. In this regard, the team working on Work Package 4 aims to develop, validate, and implement novel MRI image analysis pipelines to more effectively distinguish between active inflammation and…
